MULTIPLICATION OF NEWCASTLE DISEASE VIRUS IN TISSUE CALTURE
نویسندگان
چکیده
منابع مشابه
Efficacy of Thermostable Newcastle Disease Virus Strain I-2 in Broiler Chickens Challenged with Highly Virulent Newcastle Virus
Newcastle disease (ND) is a major threat to poultry industry production throughout developing countries. The Newcastle disease viruses (NDVs) infecting industrialized and indigenous poultry in Iran are velogenic strains and responsible for the frequent outbreaks of ND in poultry farms even in vaccinated flocks causing serious economic losses in the commercial and indigenous poultry. However, va...
متن کاملMode of action of trichothecin on multiplication of Newcastle disease virus in cultured cells.
Trichothecin (1.6 mcg/ml) completely inhibited multiplication of Newcastle disease virus in cultures of chick embryo fibroblasts infected with 50 plaque forming units/cell ; while at lower concentrations, where complete inhibition was not observed, a dose-response effect was shown by a lengthening of the lag time before the beginning of hemagglutinin synthesis. Trichothecin had no effect on fre...
متن کاملReplication of Newcastle Disease Virus
Infection of L cells with Newcastle disease virus (NDV) results in abortive replication, with the production of very few plaque-forming units (PFU) of virus per cell (W. C. Wilcox, Virology 9:30, 1959; K. Paucker et al., Virology 17:301, 1962). It is known that interferon is synthesized by L cells infected with NDV, and the possibility exists that this endogenously produced inhibitor may be res...
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The production of infectious vesicular stomatitis (VSV) and Newcastle disease virus can be completely inhibited by 2-deoxy-d-glucose in pyruvate-containing medium, if virus either grown in pyruvate-containing medium or dialyzed against phosphate-buffered saline is used for infection. Under these conditions, the synthesis of all VSV proteins is reduced. VSV RNA, which is synthesized at reduced r...
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In order to adapt LaSota strain of Newcastle disease virus (NDV) on chick embryo fibroblast (CEF) cells, 0.1 ml from LaSota vaccine produced in Razi vaccine and serum research institute inoculated to the CEF cells and was passaged five times in the CEF grown in Eagle’s minimum essential medium (MEM). First to third passages were blind but in fourth passage cytopathic effect of virus was observe...
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ژورنال
عنوان ژورنال: Uirusu
سال: 1958
ISSN: 0042-6857,1884-3433
DOI: 10.2222/jsv.8.337